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Premenstrual tension or irritability

Also known as Premenstrual Syndrome and PMS

Premenstrual syndrome (PMS) or perimenstrual syndrome is a collection of emotional symptoms, with or without physical symptoms, related to a woman's menstrual cycle. While most women of child-bearing age (up to 85%) report having experienced physical symptoms related to normal ovulatory function, such as bloating or breast tenderness, medical definitions of PMS are limited to a consistent pattern of emotional and physical symptoms occurring only during the luteal phase of the menstrual cycle that are of "sufficient severity to interfere with some aspects of life". In particular, emotional symptoms must be present consistently to diagnose PMS. The specific emotional and physical symptoms attributable to PMS vary from woman to woman, but each individual woman's pattern of symptoms is predictable, occurs consistently during the ten days prior to menses, and vanishes either shortly before or shortly after the start of menstrual flow.

Source: Wikipedia

What causes it?

The most common causes of premenstrual tension or irritability are premenstrual tension syndrome, idiopathic irregular menstrual cycle, and idiopathic painful menstruation. Other possible causes, such as drug abuse (cocaine), are more rare.


What might my doctor prescribe?

Common Tests and Procedures

Patients with premenstrual tension or irritability often receive pelvis exam, complete physical skin exam performed (ml), examination of breast, chlamydia test, depression screen, rectal examination, lipid panel and microscopic examination (bacterial smear; culture; toxicology) .

Common Medications

The most commonly prescribed drugs for patients with premenstrual tension or irritability include drospirenone / ethinyl estradiol, portia, valacyclovir (valtrex), sumatriptan (imitrex), medroxyprogesterone, fluoxetine (prozac), mefenamic acid, abacavir / lamivudine, codeine / promethazine, metaxalone (skelaxin), buspirone (buspar), ortho cyclen and carbamazepine .

Portia
$31
(28 days)
Valacyclovir (Valtrex)
$202
(21 days)
Sumatriptan (Imitrex)
$106
(21 days)
Medroxyprogesterone
$11
(28 days)
Fluoxetine (Prozac)
$13
(28 days)
Mefenamic Acid

Metaxalone (Skelaxin)
$223
(28 days)
Buspirone (Buspar)
$16
(28 days)
Ortho Cyclen
$26
(28 days)
Carbamazepine
$43
(28 days)

Who is at risk?

Groups of people at highest risk for premenstrual tension or irritability include race/ethnicity = other, age 30-44 years, sex == female and age 15-29 years. On the other hand, age 75+ years, sex == male, age 60-74 years, and age 1-4 years almost never get premenstrual tension or irritability.

Age

< 1 years
0.1x
1-4 years
0.0x
5-14 years
1.1x
15-29 years
1.8x
30-44 years
2.3x
45-59 years
0.7x
60-74 years
0.0x
75+ years
0.0x

Sex

Male
0.0x
Female
1.7x

Race/Ethnicity

Black
0.7x
Hispanic
0.3x
White
1.2x
Other
1.8x
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