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Rosiglitazone (Avandia)

Also known as Avandamet 2/500, Avandamet 1/500, Avandamet 4/1000, Avandamet 2/1000, Avandamet 4/500, Avandaryl 4/4, Avandaryl 4/2, Avandaryl 4/1, Avandaryl 8/2, and Avandaryl 8/4

Rosiglitazone (trade name Avandia, GlaxoSmithKline) is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug or in combination with metformin (trade name Avandamet) or with glimepiride (trade name Avandaryl). First released in 1999, annual sales peaked at approximately $2.5bn in 2006, but declined after the drug was found to increase risk of heart attacks. The drug's patent expired in 2012.

Source: Wikipedia

Estimated Total Cost: $156.63 for an average of 28 days supply

What is it prescribed for?

Patients are most commonly prescribed rosiglitazone to treat diabetes, diabetic peripheral neuropathy, diabetic retinopathy, and diabetic kidney disease.

What drug interactions are known?

Do not take rosiglitazone if you are taking any of the following:

Critical Interactions


Significant Interactions

What side effects are related?

Patients taking rosiglitazone most commonly experience side effects like headache, pain, and back pain.

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