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Mephenytoin

Also known as Mesantoin

Mephenytoin (marketed as Mesantoin by Novartis) is a hydantoin, used as an anticonvulsant. It was introduced approximately 10 years after phenytoin, in the late 1940s. The significant metabolite of mephenytoin is nirvanol (5-ethyl-5-phenylhydantoin), which was the first hydantoin (briefly used as a hypnotic). However, nirvanol is quite toxic and mephenytoin was only considered after other less toxic anticonvulsants had failed. It can cause potentially fatal blood dyscrasia in 1% of patients.

Source: Wikipedia

What is it prescribed for?

Patients are most commonly prescribed mephenytoin to treat blastomycosis, rabies, west nile virus, and pick disease.

What drug interactions are known?

Do not take mephenytoin if you are taking any of the following:

Critical Interactions

Significant Interactions

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