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Hydroxychloroquine (Plaquenil)

Also known as Plaquenil and Quineprox


Hydroxychloroquine is an antimalarial drug, sold under the trade names Plaquenil, Axemal (in India), Dolquine, and Quensyl, also used to reduce inflammation in the treatment of rheumatoid arthritis (see disease-modifying antirheumatic drugs) and lupus. Hydroxychloroquine differs from chloroquine by the presence of a hydroxyl group at the end of the side chain: The N-ethyl substituent is beta-hydroxylated. It is available for oral administration as hydroxychloroquine sulfate (plaquenil) of which 200 mg contains 155 mg base in chiral form. Hydroxychloroquine has similar pharmacokinetics to chloroquine, with quick gastrointestinal absorption and is eliminated by the kidney. Cytochrome P450 enzymes (CYP 2D6, 2C8, 3A4 and 3A5) N-desethylated Hydroxychloroquine to Ndesethylhydroxychloroquine.

Source: Wikipedia

Estimated Total Cost: $16.59 for an average of 28 days supply

What is it prescribed for?

Patients are most commonly prescribed hydroxychloroquine to treat systemic lupus erythematosis (sle), rheumatoid arthritis, sarcoidosis, and primary kidney disease.

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