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Guanfacine (Intuniv)

Also known as Tenex and Intuniv


Guanfacine (brand name Tenex, and the extended release Intuniv) is a sympatholytic. It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system α2A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone. Its side-effects are dose dependent, with practically no dryness of the mouth at doses of 2 mg and less.

Source: Wikipedia

Estimated Total Cost: $13.6 for an average of 28 days supply

What is it prescribed for?

Patients are most commonly prescribed guanfacine to treat attention deficit hyperactivity disorder (adhd), developmental disability, autism, and oppositional disorder.

What side effects are related?

Patients taking guanfacine most commonly experience side effects like mouth dryness, sleepiness, and abdominal pain.

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