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Guanethidine

Also known as Ganda 1+0.2, Ganda 3+0.5, Ganda 5+0.5, Ganda 5+1, Esimil, and Ismelin

Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. Guanethidine is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself (NET, uptake 1), and uptake is essential for the drug's action. Once guanethidine has entered the nerve, it is concentrated in transmitter vesicles, where it replaces norepinephrine.

Source: Wikipedia

What is it prescribed for?

Patients are most commonly prescribed guanethidine to treat blastomycosis, rabies, west nile virus, and pick disease.

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