Also known as Sandimmune, Neoral, and Sangcya
Ciclosporin (INN/BAN) , cyclosporine (USAN), cyclosporin (former BAN), or cyclosporin A (often shortened to CsA) is an immunosuppressant drug widely used in organ transplantation to prevent rejection. It reduces the activity of the immune system by interfering with the activity and growth of T cells. It was initially isolated from the fungus Tolypocladium inflatum (Beauveria nivea), found in a soil sample obtained in 1969 from Hardangervidda, Norway by Dr. Hans Peter Frey, a Sandoz biologist. Most peptides are synthesized by ribosomes, but ciclosporin is a cyclic nonribosomal peptide of 11 amino acids and contains a single D-amino acid, which are rarely encountered in nature.
Source: WikipediaEstimated Total Cost: $208.87 for an average of 28 days supply
Patients are most commonly prescribed cyclosporine to treat cardiomyopathy, chronic kidney disease, aplastic anemia, and primary kidney disease.
Critical Interactions
Significant Interactions
Patients taking cyclosporine most commonly experience side effects like hirsutism, high blood pressure, and urinary tract infection.