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Corticotropin (Acthar)

Also known as Acth Gel, Acth-40 Hp, Acth-80, and Acthar

Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency (primary adrenal insufficiency, also called Addison's disease, occurs when adrenal gland production of cortisol is chronically deficient, resulting in chronically elevated ACTH levels); when a pituitary tumor is the cause of elevated ACTH (from the anterior pituitary) this is known as Cushing's Disease and the constellation of signs and symptoms of the excess cortisol (hypercortisolism) is known as Cushing's syndrome. ACTH is also related to the circadian rhythm in many organisms.

Source: Wikipedia

Estimated Total Cost: $36813.64 for an average of 14 days supply

What is it prescribed for?

Patients are most commonly prescribed corticotropin to treat ear pain, rabies, pick disease, and west nile virus.

What drug interactions are known?

Do not take corticotropin if you are taking any of the following:

Critical Interactions


Significant Interactions

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