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Capecitabine (Xeloda)

Also known as Xeloda

Capecitabine (INN) (Xeloda, Roche) is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

Source: Wikipedia

What is it prescribed for?

Patients are most commonly prescribed capecitabine to treat colorectal cancer, breast cancer, metastatic cancer, and pancreatic cancer.

What drug interactions are known?

Do not take capecitabine if you are taking any of the following:

Critical Interactions

Significant Interactions

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