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Bupropion (Wellbutrin)

Also known as Wellbutrin and Zyban


Bupropion (/bjuːˈproʊpi.ɒn/ bew-PROH-pee-on; marketed as Wellbutrin, Zyban, Voxra, Budeprion, Prexaton, Elontril or Aplenzin; and formerly known as amfebutamone) is an atypical antidepressant and smoking cessation aid. Its chemical name is 3-chloro-N-tert-butyl-β-ketoamphetamine, a substituted cathinone (β-ketoamphetamine), as well as substituted amphetamine. The drug therefore is a mild psychostimulant. Its primary pharmacological action is norepinephrine-dopamine reuptake inhibition. It binds selectively to the dopamine transporter, but its behavioural effects have often been attributed to its inhibition of norepinephrine reuptake. It also acts as a nicotinic acetylcholine receptor antagonist. Bupropion belongs to the chemical class of aminoketones and is similar in structure to stimulants cathinone and diethylpropion, and to phenethylamines in general. Medically, bupropion serves as a non-tricyclic antidepressant fundamentally different to most commonly prescribed antidepressants such as SSRIs.

Source: Wikipedia

Estimated Total Cost: $50.85 for an average of 28 days supply

What is it prescribed for?

Patients are most commonly prescribed bupropion to treat depression, depression, bipolar disorder, and dysthymic disorder.

What drug interactions are known?

Do not take bupropion if you are taking any of the following:

Critical Interactions

Significant Interactions

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