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Alosetron (Lotronex)

Also known as Lotronex

Alosetron hydrochloride (initial brand name: Lotronex; originator: GSK) is a 5-HT3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only. It is currently marketed by Prometheus Laboratories Inc. (San Diego), also under the trade name Lotronex. Alosetron was withdrawn from the market in 2000 owing to the occurrence of serious life-threatening gastrointestinal adverse effects, but was reintroduced in 2002 with availability and use restricted.

Source: Wikipedia

Estimated Total Cost: $790.2 for an average of 28 days supply

What is it prescribed for?

Patients are most commonly prescribed alosetron to treat blastomycosis, rabies, west nile virus, and pick disease.

What drug interactions are known?

Do not take alosetron if you are taking any of the following:

Critical Interactions

Significant Interactions

What side effects are related?

Patients taking alosetron most commonly experience side effects like constipation, nausea, and abdominal pain.

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