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Uterine fibroids

Also known as Fibroids, Leiomyoma, Uterine Leiomyoma, Myofibroma, Fibromyoma, Leiomyofibroma, and Uterine Fibromyoma

A uterine fibroid is a leiomyoma (benign (non-cancerous) tumor from smooth muscle tissue) that originates from the smooth muscle layer (myometrium) of the uterus. Fibroids are often multiple and garner the designation of diffuse uterine leiomyomatosis if they are randomly located and many in numbers. There is a malignant form of a fibroid and fibroids can rarely (0.1-0.5%), undergo malignant degeneration into leiomyosarcoma. Additionally there are rare forms of fibroids where the lesions are capable of metastasising without malignant transformation and this process is called benign metastasising leiomyoma.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with uterine fibroids, 49% report having sharp abdominal pain, 42% report having pelvic pain, and 37% report having heavy menstrual flow. The symptoms that are highly suggestive of uterine fibroids are pelvic pain, heavy menstrual flow, unpredictable menstruation, painful menstruation, intermenstrual bleeding, and long menstrual periods, although you may still have uterine fibroids without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with uterine fibroids often receive pelvis exam, radiographic imaging procedure, complete blood count, urinalysis, ultrasonography, examination of breast, standard pregnancy test and mammography .

Common Medications

The most commonly prescribed drugs for patients with uterine fibroids include medroxyprogesterone, leuprolide (lupron), progesterone, clomiphene (clomid), human chorionic gonadotropin (hcg), norethindrone (loestrin fe), sevoflurane, nafarelin (synarel), butoconazole topical, goserelin (zoladex), ferrous sulfate, misoprostol and brompheniramine / hydrocodone / phenylephrine .

Who is at risk?

Groups of people at highest risk for uterine fibroids include age 30-44 years, sex == female, race/ethnicity = black and age 45-59 years. On the other hand, age 75+ years, sex == male, age 5-14 years, age 1-4 years, and age < 1 years almost never get uterine fibroids.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.0x
15-29 years
0.3x
30-44 years
2.5x
45-59 years
2.1x
60-74 years
0.2x
75+ years
0.0x

Sex

Male
0.0x
Female
1.7x

Race/Ethnicity

Black
2.4x
Hispanic
1.2x
White
0.5x
Other
1.0x
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