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Toxic multinodular goiter

Also known as Parry Disease

Toxic multinodular goiter (also known as toxic nodular goiter, toxic nodular struma) is a common cause of hyperthyroidism in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH).

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with toxic multinodular goiter, 27% report having fatigue, 19% report having abnormal involuntary movements, and 15% report having double vision. The symptoms that are highly suggestive of toxic multinodular goiter are double vision, abnormal movement of eyelid, and foreign body sensation in eye, although you may still have toxic multinodular goiter without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with toxic multinodular goiter often receive hematologic tests, complete physical skin exam performed (ml), lipid panel, ultrasonography, hemoglobin a1c measurement, examination of breast, thyroidectomy; partial or complete and excision .

Common Medications

The most commonly prescribed drugs for patients with toxic multinodular goiter include methimazole, thyroxine (synthroid), propylthiouracil, propranolol, travoprost (travatan), etodolac, trifluoperazine (stelazine), magnesium oxide, doxercalciferol (hectorol), fluorescein, naproxen / sumatriptan, benzylpenicilloyl polylysine (pre-pen) and triiodothyronine (cytomel) .

Who is at risk?

Groups of people at highest risk for toxic multinodular goiter include race/ethnicity = other age 30-44 years. On the other hand, age < 1 years almost never get toxic multinodular goiter.

Age

< 1 years
0.0x
1-4 years
0.1x
5-14 years
0.3x
15-29 years
1.1x
30-44 years
1.5x
45-59 years
1.4x
60-74 years
1.0x
75+ years
0.4x

Sex

Male
0.5x
Female
1.4x

Race/Ethnicity

Black
1.1x
Hispanic
1.0x
White
0.9x
Other
1.5x
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