Also known as Sickle Cell Pain Crisis
Sickle-cell disease (SCD), or sickle-cell anaemia (SCA) or drepanocytosis, is a hereditary blood disorder, characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications. The sickling occurs because of a mutation in the haemoglobin gene. Individuals with one copy of the defunct gene display both normal and abnormal haemoglobin. This is an example of codominance.Source: Wikipedia
Within all the people who go to their doctor with sickle cell crisis, 73% report having ache all over, 71% report having leg pain, and 68% report having back pain. The symptoms that are highly suggestive of sickle cell crisis are ache all over, although you may still have sickle cell crisis without those symptoms.
Patients with sickle cell crisis often receive hematologic tests, complete blood count, intravenous fluid replacement, radiographic imaging procedure, plain x-ray, kidney function tests, electrolytes panel and glucose measurement .
The most commonly prescribed drugs for patients with sickle cell crisis include hydromorphone (dilaudid), diphenhydramine (benadryl), morphine (rms), folic acid, meperidine (demerol), hydroxyurea, lvp solution, magaldrate, potassium bicarbonate, scopolamine, buprenorphine (suboxone), cefotaxime and meperidine / promethazine .
Groups of people at highest risk for sickle cell crisis include age 30-44 years, race/ethnicity = black and age 15-29 years. On the other hand, age 75+ years, age 60-74 years, and race/ethnicity = white almost never get sickle cell crisis.