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Sarcoidosis

Also known as Sarcoid, Schaumann Disease, and Boeck's Sarcoid

Sarcoidosis (from sarc meaning "flesh", -oid, "like", and -osis, "diseased or abnormal condition"), also called sarcoid, Besnier-Boeck disease or Besnier-Boeck-Schaumann disease, is a syndrome involving abnormal collections of chronic inflammatory cells (granulomas) that can form as nodules in multiple organs. The granulomas that appear are usually not of the caseating variety and are most often located in the lungs or the lymph nodes, but virtually any organ can be affected. Onset is usually gradual. Sarcoidosis may be asymptomatic or chronic. It commonly improves or clears up spontaneously. More than two-thirds of people with lung sarcoidosis have no symptoms after 9 years. About 50% have relapses. About 10% develop serious disability. Lung scarring or infection may lead to respiratory failure and death. In chronic cases, symptoms may fluctuate over many years. The causes of sarcoidosis are not completely understood.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with sarcoidosis, 53% report having cough, 46% report having shortness of breath, and 28% report having fatigue.


What might my doctor prescribe?

Common Tests and Procedures

Patients with sarcoidosis often receive hematologic tests, radiographic imaging procedure, complete blood count, plain x-ray, electrocardiogram, complete physical skin exam performed (ml), magnetic resonance imaging and biopsy .

Common Medications

The most commonly prescribed drugs for patients with sarcoidosis include prednisone, fluticasone / salmeterol, hydroxychloroquine (plaquenil), methotrexate, azathioprine, risedronate (actonel), ursodiol (urso), bosentan (tracleer), salmeterol, sotalol, bumetanide, ibandronate (boniva) and tacrolimus (prograf) .

Prednisone
$5
(28 days)
Hydroxychloroquine (Plaquenil)
$17
(28 days)
Methotrexate
$14
(28 days)
Azathioprine
$28
(28 days)
Risedronate (Actonel)
$104
(28 days)
Ursodiol (Urso)

Bosentan (Tracleer)
$5485
(28 days)
Salmeterol
$142
(28 days)
Sotalol
$19
(28 days)
Bumetanide
$11
(28 days)
Ibandronate (Boniva)
$105
(28 days)
Tacrolimus (Prograf)
$376
(28 days)

Who is at risk?

Groups of people at highest risk for sarcoidosis include race/ethnicity = other, age 30-44 years, race/ethnicity = black and age 45-59 years. On the other hand, age 1-4 years and age < 1 years almost never get sarcoidosis.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.1x
15-29 years
0.1x
30-44 years
1.8x
45-59 years
2.0x
60-74 years
1.2x
75+ years
0.4x

Sex

Male
0.9x
Female
1.1x

Race/Ethnicity

Black
2.7x
Hispanic
0.7x
White
0.5x
Other
1.6x
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