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Restless leg syndrome

Also known as Ekbom Syndrome

Restless Legs Syndrome (RLS), also known as Willis-Ekbom disease (WED), is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, head, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with restless leg syndrome, 77% report having abnormal involuntary movements, 49% report having leg pain, and 39% report having headache. The symptoms that are highly suggestive of restless leg syndrome are abnormal involuntary movements, sleepiness, and apnea, although you may still have restless leg syndrome without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with restless leg syndrome often receive other diagnostic procedures (interview; evaluation; consultation), lipid panel, hemoglobin a1c measurement, other therapeutic procedures on eyelids; conjunctiva; cornea, magnetic resonance imaging, examination of foot, depression screen and bone density scan .

Common Medications

The most commonly prescribed drugs for patients with restless leg syndrome include ropinirole, pramipexole (mirapex), gabapentin, carbidopa / levodopa, modafinil (provigil), tizanidine, rizatriptan (maxalt), sitagliptin (januvia), ramelteon (rozerem), primidone, doxepin, solifenacin (vesicare) and entecavir (baraclude) .

Ropinirole
$41
(28 days)
Pramipexole (Mirapex)
$121
(28 days)
Gabapentin
$25
(28 days)
Modafinil (Provigil)
$596
(28 days)
Tizanidine
$25
(28 days)
Rizatriptan (Maxalt)
$262
(21 days)
Sitagliptin (Januvia)
$177
(28 days)
Ramelteon (Rozerem)
$128
(28 days)
Primidone
$29
(28 days)
Doxepin
$10
(28 days)
Solifenacin (Vesicare)
$129
(28 days)
Entecavir (Baraclude)
$690
(28 days)

Who is at risk?

Groups of people at highest risk for restless leg syndrome include age 60-74 years age 45-59 years. On the other hand, age 1-4 years almost never get restless leg syndrome.

Age

< 1 years
0.1x
1-4 years
0.0x
5-14 years
0.3x
15-29 years
0.3x
30-44 years
0.9x
45-59 years
1.7x
60-74 years
1.9x
75+ years
1.4x

Sex

Male
0.9x
Female
1.1x

Race/Ethnicity

Black
0.4x
Hispanic
0.5x
White
1.3x
Other
0.8x
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