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Peyronie disease

Also known as Penile Fibrosis and Induratio Penis Plastica

Peyronie's Disease (also known as "Induratio penis plastica", or more recently Chronic Inflammation of the Tunica Albuginea (CITA), is a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting up to 10% of men. Specifically, scar tissue forms in the tunica albuginea, the thick sheath of tissue surrounding the corpora cavernosa causing pain, abnormal curvature, erectile dysfunction, indentation, loss of girth and shortening. A variety of treatments have been used, but none have been especially effective.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with peyronie disease, 67% report having impotence, 58% report having penis pain, and 34% report having symptoms of prostate. The symptoms that are highly suggestive of peyronie disease are impotence, penis pain, symptoms of prostate, mass in scrotum, sweating, infertility, warts, bumps on penis, and emotional symptoms, although you may still have peyronie disease without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with peyronie disease often receive urinalysis, rectal examination, prostate specific antigen measurement, complete physical skin exam performed (ml), other diagnostic procedures (interview; evaluation; consultation), depression screen, other or therapeutic procedures; male genital and endoscopy and endoscopic biopsy of the urinary tract .

Common Medications

The most commonly prescribed drugs for patients with peyronie disease include vitamin e (vita-e), pentoxifylline, sildenafil (viagra), verapamil (univer), tamsulosin (flomax), olmesartan (benicar), fenofibrate (tricor), potassium aminobenzoate (potaba), hydrochlorothiazide / propranolol, quinidine, halobetasol topical, indapamide and alfuzosin (uroxatral) .

Who is at risk?

Groups of people at highest risk for peyronie disease include sex == male, age 60-74 years and age 45-59 years. On the other hand, race/ethnicity = other, age 5-14 years, age 1-4 years, sex == female, and age < 1 years almost never get peyronie disease.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.0x
15-29 years
0.6x
30-44 years
0.6x
45-59 years
1.7x
60-74 years
2.5x
75+ years
0.5x

Sex

Male
2.4x
Female
0.0x

Race/Ethnicity

Black
0.6x
Hispanic
0.5x
White
1.3x
Other
0.0x
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