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Neuromyelitis optica

Also known as Devic Disease

Neuromyelitis optica (NMO), also known as Devic's disease or Devic's syndrome, is an autoimmune, inflammatory disorder in which a person's own immune system attacks the optic nerves and spinal cord. This produces an inflammation of the optic nerve (optic neuritis) and the spinal cord (myelitis). Although inflammation may also affect the brain, the lesions are different from those observed in the related condition, multiple sclerosis. Spinal cord lesions lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation (including blindness), and/or bladder and bowel dysfunction.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with neuromyelitis optica, 77% report having painful urination, 77% report having diminished vision, and 77% report having arm pain. The symptoms that are highly suggestive of neuromyelitis optica are painful urination, ache all over, arm pain, loss of sensation, weakness, diminished vision, vulvar sore, excessive growth, knee lump or mass, nailbiting, shoulder swelling, and neck cramps or spasms, although you may still have neuromyelitis optica without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with neuromyelitis optica often receive hematologic tests, magnetic resonance imaging, other diagnostic procedures (interview; evaluation; consultation), urinalysis, radiographic imaging procedure, corneal transplant, transurethral resection of prostate (turp) and coronary thrombolysis .

Common Medications

The most commonly prescribed drugs for patients with neuromyelitis optica include azathioprine, baclofen, carbamazepine, polyethylene glycol 3350 (miralax), pregabalin (lyrica), nitrofurantoin, paroxetine (paxil), docusate (colace), oxycodone, gabapentin, ciprofloxacin, chlorpheniramine / phenindamine / phenylpropanolamine and air .

Azathioprine
$28
(28 days)
Baclofen
$18
(28 days)
Carbamazepine
$43
(28 days)
Polyethylene Glycol 3350 (Miralax)
$30
(28 days)
Pregabalin (Lyrica)
$148
(28 days)
Nitrofurantoin
$28
(21 days)
Paroxetine (Paxil)
$19
(28 days)
Docusate (Colace)
$3
(21 days)
Oxycodone
$193
(21 days)
Gabapentin
$25
(28 days)
Ciprofloxacin
$7
(7 days)
Air

Who is at risk?

Groups of people at highest risk for neuromyelitis optica include race/ethnicity = black age 15-29 years.

Age

< 1 years
0.4x
1-4 years
0.2x
5-14 years
0.1x
15-29 years
2.6x
30-44 years
1.4x
45-59 years
1.2x
60-74 years
0.1x
75+ years
0.1x

Sex

Male
0.6x
Female
1.3x

Race/Ethnicity

Black
2.6x
Hispanic
0.1x
White
0.8x
Other
0.2x
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