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Myelodysplastic syndrome

Also known as Myelodysplasia

The myelodysplastic syndromes (MDS, formerly known as preleukemia) are a diverse collection of hematological (blood-related) medical conditions that involve ineffective production (or dysplasia) of the myeloid class of blood cells.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with myelodysplastic syndrome, 50% report having fatigue, 11% report having chills, and 6% report having difficulty speaking.


What might my doctor prescribe?

Common Tests and Procedures

Patients with myelodysplastic syndrome often receive hematologic tests, complete blood count, glucose measurement, hemoglobin a1c measurement, biopsy, bone marrow biopsy, prostate specific antigen measurement and ophthalmic examination and evaluation .

Common Medications

The most commonly prescribed drugs for patients with myelodysplastic syndrome include darbepoetin alfa (aranesp), epoetin alfa (procrit), vitamin b 12, decitabine, tiotropium (spiriva), deferasirox (exjade), lactulose, sennosides, usp (perdiem), filgrastim (neupogen), granisetron, hydroxychloroquine (plaquenil), melphalan and dexamethasone .

Darbepoetin Alfa (Aranesp)
$1004
(21 days)
Epoetin Alfa (Procrit)
$804
(21 days)
Vitamin B 12
$6
(28 days)
Decitabine

Tiotropium (Spiriva)
$180
(28 days)
Deferasirox (Exjade)
$4742
(28 days)
Lactulose
$24
(21 days)
Sennosides, Usp (Perdiem)
$9
(28 days)
Filgrastim (Neupogen)
$1938
(14 days)
Granisetron
$426
(14 days)
Hydroxychloroquine (Plaquenil)
$17
(28 days)
Melphalan
$148
(14 days)
Dexamethasone
$13
(14 days)

Who is at risk?

Groups of people at highest risk for myelodysplastic syndrome include age 75+ years age 60-74 years. On the other hand, age 15-29 years and age < 1 years almost never get myelodysplastic syndrome.

Age

< 1 years
0.0x
1-4 years
0.2x
5-14 years
0.3x
15-29 years
0.0x
30-44 years
0.1x
45-59 years
0.1x
60-74 years
3.1x
75+ years
4.9x

Sex

Male
1.3x
Female
0.8x

Race/Ethnicity

Black
0.4x
Hispanic
0.4x
White
1.4x
Other
0.5x
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