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Lewy body dementia

Also known as Lewy Body Disease

Dementia with Lewy bodies (DLB), also known under a variety of other names including Lewy body dementia, diffuse Lewy body disease, cortical Lewy body disease, and senile dementia of Lewy type, is a type of dementia closely associated with both Alzheimer's and Parkinson's diseases. It is characterized anatomically by the presence of Lewy bodies, clumps of alpha-synuclein and ubiquitin protein in neurons, detectable in post mortem brain histology. Lewy body dementia affects 1.3 million individuals in the United States alone.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with lewy body dementia, 68% report having disturbance of memory, 59% report having delusions or hallucinations, and 53% report having problems with movement. The symptoms that are highly suggestive of lewy body dementia are disturbance of memory, delusions or hallucinations, abnormal involuntary movements, problems with movement, and hostile behavior, although you may still have lewy body dementia without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with lewy body dementia often receive radiographic imaging procedure, x-ray computed tomography, other diagnostic procedures (interview; evaluation; consultation), cardiac enzymes measurement, blood culture, cat scan of head, cardiac monitoring and magnetic resonance imaging .

Common Medications

The most commonly prescribed drugs for patients with lewy body dementia include carbidopa / levodopa, memantine (namenda), donepezil (aricept), rivastigmine (exelon), quetiapine (seroquel), raloxifene (evista), pramipexole (mirapex), ropinirole, nifedipine, vitamin b 12, entacapone (comtan), selegiline and hydrochlorothiazide / spironolactone .

Memantine (Namenda)
$157
(28 days)
Donepezil (Aricept)
$210
(28 days)
Rivastigmine (Exelon)
$204
(28 days)
Quetiapine (Seroquel)
$290
(28 days)
Raloxifene (Evista)
$105
(28 days)
Pramipexole (Mirapex)
$121
(28 days)
Ropinirole
$41
(28 days)
Nifedipine
$39
(28 days)
Vitamin B 12
$6
(28 days)
Entacapone (Comtan)
$296
(28 days)
Selegiline
$120
(28 days)

Who is at risk?

Groups of people at highest risk for lewy body dementia include age 75+ years age 60-74 years. On the other hand, age 30-44 years, age 5-14 years, age 1-4 years, age 15-29 years, and age < 1 years almost never get lewy body dementia.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.0x
15-29 years
0.0x
30-44 years
0.0x
45-59 years
0.2x
60-74 years
2.1x
75+ years
6.9x

Sex

Male
1.1x
Female
0.9x

Race/Ethnicity

Black
0.3x
Hispanic
0.9x
White
1.3x
Other
0.5x
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