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Hypercalcemia

Hypercalcaemia (British English) or hypercalcemia (American English) is an elevated calcium (Ca+) level in the blood. (Normal range: 9–10.5 mg/dL or 2.2–2.6 mmol/L). It can be an asymptomatic laboratory finding, but because an elevated calcium level is often indicative of other diseases, a workup should be undertaken if it persists. It can be due to excessive skeletal calcium release, increased intestinal calcium absorption, or decreased renal calcium excretion.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with hypercalcemia, 39% report having weakness, 28% report having dizziness, and 20% report having loss of sensation. The symptoms that are highly suggestive of hypercalcemia are hand or finger weakness, arm cramps or spasms, and irregular appearing nails, although you may still have hypercalcemia without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with hypercalcemia often receive hematologic tests, complete blood count, glucose measurement, urinalysis, electrolytes panel, electrocardiogram, complete physical skin exam performed (ml) and lipid panel .

Common Medications

The most commonly prescribed drugs for patients with hypercalcemia include ergocalciferol, zoledronic acid (reclast), tacrolimus (prograf), potassium citrate, ibandronate (boniva), oxcarbazepine (trileptal), donepezil (aricept), estradiol, benzocaine/butamben/tetracaine topical, glimepiride / pioglitazone, mefloquine, doxercalciferol (hectorol) and suprofen ophthalmic .

Ergocalciferol
$6
(28 days)
Zoledronic Acid (Reclast)
$835
(28 days)
Tacrolimus (Prograf)
$376
(28 days)
Potassium Citrate
$38
(28 days)
Ibandronate (Boniva)
$105
(28 days)
Oxcarbazepine (Trileptal)
$95
(28 days)
Donepezil (Aricept)
$210
(28 days)
Estradiol
$29
(28 days)
Mefloquine
$34
(28 days)
Doxercalciferol (Hectorol)
$345
(28 days)
Suprofen Ophthalmic

Who is at risk?

Groups of people at highest risk for hypercalcemia include race/ethnicity = other, age 75+ years and age 60-74 years. On the other hand, age < 1 years almost never get hypercalcemia.

Age

< 1 years
0.0x
1-4 years
0.2x
5-14 years
0.1x
15-29 years
0.2x
30-44 years
0.7x
45-59 years
1.2x
60-74 years
2.1x
75+ years
2.7x

Sex

Male
0.6x
Female
1.3x

Race/Ethnicity

Black
0.8x
Hispanic
0.4x
White
1.1x
Other
1.6x
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