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Hepatitis due to a toxin

Also known as Toxic Hepatitis

INFLAMMATION of the LIVER due to hepatocellular toxicity, caused by drug metabolites and chemicals from the environment.

Source: MeSH

What are the symptoms?

Within all the people who go to their doctor with hepatitis due to a toxin, 53% report having sharp abdominal pain, 33% report having diarrhea, and 33% report having nausea. The symptoms that are highly suggestive of hepatitis due to a toxin are jaundice, although you may still have hepatitis due to a toxin without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with hepatitis due to a toxin often receive hematologic tests, complete blood count, glucose measurement, electrolytes panel, urinalysis, kidney function tests, intravenous fluid replacement and liver function tests .

Common Medications

The most commonly prescribed drugs for patients with hepatitis due to a toxin include kaletra, atazanavir (reyataz), ritonavir (norvir), lamivudine, azathioprine, emtricitabine-tenofovir, mycophenolate mofetil (cellcept), stavudine (zerit), zidovudine, ethambutol, didanosine (videx), abacavir / lamivudine and tacrolimus (prograf) .

Kaletra
$693
(28 days)
Atazanavir (Reyataz)
$880
(28 days)
Ritonavir (Norvir)
$345
(28 days)
Lamivudine
$292
(28 days)
Azathioprine
$28
(28 days)
Emtricitabine-Tenofovir

Mycophenolate Mofetil (Cellcept)
$263
(28 days)
Stavudine (Zerit)
$138
(28 days)
Zidovudine
$62
(28 days)
Ethambutol
$80
(28 days)
Didanosine (Videx)
$203
(28 days)
Tacrolimus (Prograf)
$376
(28 days)

Who is at risk?

Groups of people at highest risk for hepatitis due to a toxin include race/ethnicity = other age 45-59 years.

Age

< 1 years
0.2x
1-4 years
0.1x
5-14 years
1.1x
15-29 years
0.8x
30-44 years
1.0x
45-59 years
1.9x
60-74 years
1.0x
75+ years
0.3x

Sex

Male
1.2x
Female
0.9x

Race/Ethnicity

Black
1.4x
Hispanic
1.4x
White
0.7x
Other
1.8x
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