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Gastroduodenal ulcer

Also known as PUD and Peptic Ulcer Disease

A peptic ulcer, also known as peptic ulcer disease (PUD), is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm. As many as 70–90% of such ulcers are associated with Helicobacter pylori, a helical-shaped bacterium that lives in the acidic environment of the stomach; however, only 40% of those cases go to a doctor. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with gastroduodenal ulcer, 79% report having sharp abdominal pain, 52% report having vomiting, and 51% report having nausea. The symptoms that are highly suggestive of gastroduodenal ulcer are upper abdominal pain, vomiting blood, blood in stool, changes in stool appearance, melena, and heartburn, although you may still have gastroduodenal ulcer without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with gastroduodenal ulcer often receive hematologic tests, complete blood count, radiographic imaging procedure, glucose measurement, intravenous fluid replacement, electrolytes panel, urinalysis and kidney function tests .

Common Medications

The most commonly prescribed drugs for patients with gastroduodenal ulcer include pantoprazole, esomeprazole (nexium), famotidine, aluminum hydroxide / magnesium hydroxide, sucralfate (carafate), atropine / hyoscyamine / phenobarbital / scopolamine, misoprostol, simethicone (degas), arginine, silver topical, octreotide, bismuth subsalicylate (pepto-bismol) and droperidol .

Pantoprazole
$110
(28 days)
Esomeprazole (Nexium)
$168
(28 days)
Famotidine
$10
(28 days)
Sucralfate (Carafate)
$49
(28 days)
Misoprostol
$45
(28 days)
Simethicone (Degas)
$7
(21 days)
Arginine

Silver Topical

Octreotide
$1745
(21 days)
Bismuth Subsalicylate (Pepto-Bismol)
$6
(14 days)
Droperidol
$19
(21 days)

Who is at risk?

Groups of people at highest risk for gastroduodenal ulcer include age 75+ years. On the other hand, age 1-4 years and age < 1 years almost never get gastroduodenal ulcer.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.2x
15-29 years
0.8x
30-44 years
1.0x
45-59 years
1.4x
60-74 years
1.3x
75+ years
1.6x

Sex

Male
1.0x
Female
1.0x

Race/Ethnicity

Black
0.9x
Hispanic
1.1x
White
1.0x
Other
1.3x
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