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Erythema multiforme

Also known as Erythema Polymorphe

Erythema multiforme is a skin condition of unknown cause, possibly mediated by deposition of immune complex (mostly IgM) in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure. It is a common disorder, with peak incidence in the second and third decades of life.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with erythema multiforme, 92% report having skin rash, 67% report having fever, and 44% report having itching of skin. The symptoms that are highly suggestive of erythema multiforme are skin rash, itching of skin, mouth ulcer, and skin pain, although you may still have erythema multiforme without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with erythema multiforme often receive complete physical skin exam performed (ml), glucose measurement, electrolytes panel, kidney function tests, intravenous fluid replacement, liver function tests, insertion of catheter into urinary bladder and blood culture .

Common Medications

The most commonly prescribed drugs for patients with erythema multiforme include diphenhydramine (benadryl), prednisolone, hydroxyzine, reserpine (hhr), mineral oil (stye), selenium sulfide topical, hydralazine, clotrimazole topical, labetalol, erythromycin, acyclovir, chlorpheniramine / phenindamine / phenylpropanolamine and mecamylamine .

Who is at risk?

Groups of people at highest risk for erythema multiforme include race/ethnicity = other, age 5-14 years, age 1-4 years and age < 1 years. On the other hand, age 75+ years and age 60-74 years almost never get erythema multiforme.

Age

< 1 years
4.4x
1-4 years
4.3x
5-14 years
2.4x
15-29 years
0.4x
30-44 years
0.9x
45-59 years
0.7x
60-74 years
0.0x
75+ years
0.0x

Sex

Male
1.0x
Female
1.0x

Race/Ethnicity

Black
0.7x
Hispanic
1.1x
White
0.9x
Other
2.3x
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