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Endometrial cancer

Also known as Endometrial Adenocarcinoma

Endometrial cancer refers to several types of malignancies that arise from the endometrium, or lining, of the uterus. Endometrial cancers are the most common gynecologic cancers in the United States, with over 35,000 women diagnosed each year. The incidence is on a slow rise secondary to the obesity epidemic. The most common subtype, endometrioid adenocarcinoma, typically occurs within a few decades of menopause, is associated with obesity, excessive estrogen exposure, often develops in the setting of endometrial hyperplasia, and presents most often with vaginal bleeding. Endometrial carcinoma is the third most common cause of gynecologic cancer death (behind ovarian and cervical cancer). A total abdominal hysterectomy (surgical removal of the uterus) with bilateral salpingo-oophorectomy is the most common therapeutic approach.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with endometrial cancer, 76% report having vaginal bleeding after menopause, 32% report having intermenstrual bleeding, and 15% report having long menstrual periods. The symptoms that are highly suggestive of endometrial cancer are vaginal bleeding after menopause, intermenstrual bleeding, hot flashes, long menstrual periods, infrequent menstruation, and mass on vulva, although you may still have endometrial cancer without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with endometrial cancer often receive pelvis exam, radiographic imaging procedure, biopsy, examination of breast, ultrasonography, other diagnostic procedures; female organs, mammography and excision .

Common Medications

The most commonly prescribed drugs for patients with endometrial cancer include medroxyprogesterone, estrogens, conjugated (usp) (premarin), propofol, fosinopril, latanoprost, sevoflurane, megestrol (megace), progesterone, triamterene, atropine (uaa), brimonidine ophthalmic, penbutolol (levatol) and thiopental (pentothal) .

Who is at risk?

Groups of people at highest risk for endometrial cancer include age 60-74 years, sex == female and age 45-59 years. On the other hand, sex == male, age 5-14 years, age 1-4 years, and age < 1 years almost never get endometrial cancer.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.0x
15-29 years
0.1x
30-44 years
0.1x
45-59 years
2.6x
60-74 years
2.4x
75+ years
1.0x

Sex

Male
0.0x
Female
1.7x

Race/Ethnicity

Black
1.3x
Hispanic
0.7x
White
0.9x
Other
1.3x
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