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Cushing syndrome

Cushing's syndrome describes the signs and symptoms associated with prolonged exposure to inappropriately high levels of the hormone cortisol. This can be caused by taking glucocorticoid drugs, or diseases that result in excess cortisol, adrenocorticotropic hormone (ACTH), or CRH levels.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with cushing syndrome, 34% report having decreased heart rate, 34% report having weight gain, and 34% report having shoulder pain. The symptoms that are highly suggestive of cushing syndrome are decreased heart rate, weight gain, nailbiting, elbow cramps or spasms, emotional symptoms, elbow weakness, muscle swelling, itching of scrotum, infrequent menstruation, low back weakness, and bladder mass, although you may still have cushing syndrome without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with cushing syndrome often receive hematologic tests, electrolytes panel, magnetic resonance imaging, complete physical skin exam performed (ml), glucose measurement, ophthalmic examination and evaluation, depression screen and psychological and psychiatric evaluation and therapy .

Common Medications

The most commonly prescribed drugs for patients with cushing syndrome include hydrocortisone topical, prednisone, ergocalciferol, menthol topical, octreotide, vitamin a, etanercept (enbrel), azathioprine, zoledronic acid (reclast), hyzaar, methotrexate, gemfibrozil and donepezil (aricept) .

Hydrocortisone Topical

Prednisone
$5
(28 days)
Ergocalciferol
$6
(28 days)
Menthol Topical

Octreotide
$1745
(21 days)
Vitamin A
$2
(28 days)
Etanercept (Enbrel)
$1760
(28 days)
Azathioprine
$28
(28 days)
Zoledronic Acid (Reclast)
$835
(28 days)
Hyzaar
$67
(28 days)
Methotrexate
$14
(28 days)
Gemfibrozil
$18
(28 days)
Donepezil (Aricept)
$210
(28 days)

Who is at risk?

Groups of people at highest risk for cushing syndrome include race/ethnicity = other age 30-44 years. On the other hand, age 1-4 years almost never get cushing syndrome.

Age

< 1 years
0.1x
1-4 years
0.0x
5-14 years
1.1x
15-29 years
0.3x
30-44 years
1.8x
45-59 years
1.4x
60-74 years
1.3x
75+ years
0.5x

Sex

Male
0.7x
Female
1.2x

Race/Ethnicity

Black
0.5x
Hispanic
1.0x
White
1.0x
Other
2.7x
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