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Crohn disease

Also known as Granulomatous Enteritis

Crohn's disease, also known as Crohn syndrome and regional enteritis, is a type of inflammatory bowel disease that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is at its worst), vomiting (can be continuous), or weight loss, but may also cause complications outside the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration. Crohn's disease is caused by interactions between environmental, immunological and bacterial factors in genetically susceptible individuals. This results in a chronic inflammatory disorder, in which the body's immune system attacks the gastrointestinal tract possibly directed at microbial antigens. Crohn's disease has wrongly been described as an autoimmune disease in the past; recent investigators have described it as an immune deficiency state.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with crohn disease, 74% report having sharp abdominal pain, 42% report having diarrhea, and 38% report having vomiting.


What might my doctor prescribe?

Common Tests and Procedures

Patients with crohn disease often receive hematologic tests, complete blood count, urinalysis, glucose measurement, intravenous fluid replacement, kidney function tests, electrolytes panel and x-ray computed tomography .

Common Medications

The most commonly prescribed drugs for patients with crohn disease include mesalamine (asacol), infliximab (remicade), azathioprine, metronidazole, vitamin b 12, sulfasalazine, mercaptopurine, loperamide (imodium), budesonide, dicyclomine, adalimumab (humira), atropine / diphenoxylate and methotrexate .

Mesalamine (Asacol)
$300
(28 days)
Infliximab (Remicade)
$2995
(28 days)
Azathioprine
$28
(28 days)
Metronidazole
$29
(14 days)
Vitamin B 12
$6
(28 days)
Sulfasalazine
$20
(28 days)
Mercaptopurine
$76
(28 days)
Loperamide (Imodium)
$8
(14 days)
Budesonide
$281
(28 days)
Dicyclomine
$9
(28 days)
Adalimumab (Humira)
$1859
(28 days)
Methotrexate
$14
(28 days)

Who is at risk?

Groups of people at highest risk for crohn disease include age 30-44 years. On the other hand, age 1-4 years and age < 1 years almost never get crohn disease.

Age

< 1 years
0.0x
1-4 years
0.0x
5-14 years
0.6x
15-29 years
1.4x
30-44 years
1.6x
45-59 years
1.1x
60-74 years
0.9x
75+ years
0.4x

Sex

Male
1.0x
Female
1.0x

Race/Ethnicity

Black
0.6x
Hispanic
0.7x
White
1.2x
Other
0.2x
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