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Cirrhosis

Also known as Liver Cirrhosis, Cirrhosis Of Liver, and Hepatic Cirrhosis

Cirrhosis /sɪˈroʊsɪs/ is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules (lumps that occur as a result of a process in which damaged tissue is regenerated), leading to loss of liver function. Cirrhosis is most commonly caused by alcoholism, hepatitis B and hepatitis C, and fatty liver disease, but has many other possible causes. Some cases are idiopathic (i.e., of unknown cause).

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with cirrhosis, 39% report having sharp abdominal pain, 30% report having shortness of breath, and 24% report having peripheral edema. The symptoms that are highly suggestive of cirrhosis are abdominal distention, stomach bloating, and symptoms of the kidneys, although you may still have cirrhosis without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with cirrhosis often receive hematologic tests, complete blood count, glucose measurement, electrolytes panel, lipid panel, liver function tests, hemoglobin a1c measurement and ultrasonography .

Common Medications

The most commonly prescribed drugs for patients with cirrhosis include furosemide, spironolactone, lactulose, tacrolimus (prograf), nadolol, mycophenolate mofetil (cellcept), propranolol, thiamine, methadone, ursodiol (urso), epoetin alfa (procrit), peginterferon alfa-2b (sylatron) and zinc sulfate .

Furosemide
$4
(28 days)
Spironolactone
$11
(28 days)
Lactulose
$24
(21 days)
Tacrolimus (Prograf)
$376
(28 days)
Nadolol
$13
(28 days)
Mycophenolate Mofetil (Cellcept)
$263
(28 days)
Propranolol
$18
(28 days)
Thiamine
$3
(28 days)
Methadone
$20
(28 days)
Ursodiol (Urso)

Epoetin Alfa (Procrit)
$804
(21 days)
Peginterferon Alfa-2B (Sylatron)
$2177
(28 days)
Zinc Sulfate
$4
(28 days)

Who is at risk?

Groups of people at highest risk for cirrhosis include race/ethnicity = hispanic, age 60-74 years and age 45-59 years.

Age

< 1 years
0.2x
1-4 years
0.1x
5-14 years
0.1x
15-29 years
0.1x
30-44 years
0.7x
45-59 years
2.6x
60-74 years
1.7x
75+ years
0.5x

Sex

Male
1.4x
Female
0.7x

Race/Ethnicity

Black
0.7x
Hispanic
1.6x
White
0.9x
Other
1.4x
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