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Chagas disease

Also known as T Cruzi, American Trypanosomiasis, South American Trypanosomiasis, and Infection By Trypanosoma Cruzi

Chagas disease (/ˈʃɑːɡəs/; Portuguese: doença de Chagas , Spanish: enfermedad de Chagas , also known as mal de Chagas in both languages; also called American trypanosomiasis) is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi. T. cruzi is commonly transmitted to humans and other mammals by an insect vector, the blood-sucking "kissing bugs" of the subfamily Triatominae (family Reduviidae), most commonly from species belonging to the Triatoma, Rhodnius, and Panstrongylus genera.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with chagas disease, 32% report having preoccupation with sex, 32% report having wrist cramps or spasms, and 32% report having joint cramps or spasms. The symptoms that are highly suggestive of chagas disease are shoulder cramps or spasms, joint stiffness or tightness, and knee lump or mass, although you may still have chagas disease without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with chagas disease often receive plain x-ray, radiographic imaging procedure, corneal transplant, transurethral resection of prostate (turp), coronary thrombolysis, control of epistaxis, ct scan abdomen and procedures on spleen .

Common Medications

The most commonly prescribed drugs for patients with chagas disease include bactrim, chlorpheniramine / phenindamine / phenylpropanolamine, air, mecamylamine, troleandomycin, indium oxyquinoline in-111 (indium in-111 oxyquinoline), pipecuronium (arduan), grepafloxacin (raxar), rabbit anti-human t-lymphocyte globulin (thymoglobulin), iopanoic acid, conjugated estrogens topical, malathion topical and gemtuzumab (mylotarg) .

Who is at risk?

Groups of people at highest risk for chagas disease include race/ethnicity = hispanic, sex == female and age 15-29 years.

Age

< 1 years
1.4x
1-4 years
0.7x
5-14 years
0.5x
15-29 years
5.0x
30-44 years
0.2x
45-59 years
0.2x
60-74 years
0.3x
75+ years
0.5x

Sex

Male
0.1x
Female
1.7x

Race/Ethnicity

Black
0.2x
Hispanic
6.5x
White
0.1x
Other
0.9x
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