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Behcet disease

Behcet's syndrome is a disease that involves inflammation of the blood vessels. It causes problems in many parts of the body. The most common symptoms are

  • Sores in the mouth
  • Sores on the sex organs
  • Other skin sores
  • Swelling of parts of the eye
  • Pain, swelling and stiffness of the joints

More serious problems can include meningitis, blood clots, inflammation of the digestive system and blindness.

Doctors aren't sure what causes Behcet's. It is rare in the United States, but is common in the Middle East and Asia. It mainly affects people in their 20s and 30s. Diagnosing Behcet's can take a long time, because symptoms may come and go, and it may take months or even years to have all of the symptoms. There is no cure. Treatment focuses on reducing pain and preventing serious problems.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Source: MedlinePlus

What are the symptoms?

Within all the people who go to their doctor with behcet disease, 47% report having blindness, 47% report having mouth ulcer, and 47% report having upper abdominal pain. The symptoms that are highly suggestive of behcet disease are upper abdominal pain, mouth ulcer, and blindness, although you may still have behcet disease without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with behcet disease often receive diagnostic procedures on nose; mouth and pharynx, other therapeutic procedures, biopsy, excision, psychotherapy, corneal transplant, procedures on spleen and removal of ectopic pregnancy .

Common Medications

The most commonly prescribed drugs for patients with behcet disease include alendronate, lidocaine, calcifediol, ferric subsulfate topical, iopamidol (isovue), clorazepate, infliximab (remicade), tacrolimus (prograf), budesonide nasal product, epinephrine / lidocaine, atropine / hyoscyamine / phenobarbital / scopolamine, ropinirole and vitamin e (vita-e) .

Who is at risk?

Groups of people at highest risk for behcet disease include age 30-44 years, age 60-74 years and sex == female. On the other hand, race/ethnicity = hispanic, age 75+ years, and age 5-14 years almost never get behcet disease.

Age

< 1 years
0.1x
1-4 years
0.1x
5-14 years
0.0x
15-29 years
0.8x
30-44 years
1.7x
45-59 years
1.1x
60-74 years
2.2x
75+ years
0.0x

Sex

Male
0.2x
Female
1.6x

Race/Ethnicity

Black
1.2x
Hispanic
0.0x
White
1.3x
Other
0.1x
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