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Acanthosis nigricans

Acanthosis nigricans is a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the axilla, groin, umbilicus, forehead, and other areas.

Source: Wikipedia

What are the symptoms?

Within all the people who go to their doctor with acanthosis nigricans, 78% report having weight gain, 34% report having skin lesion, and 17% report having infertility. The symptoms that are highly suggestive of acanthosis nigricans are weight gain, infertility, and unwanted hair, although you may still have acanthosis nigricans without those symptoms.


What might my doctor prescribe?

Common Tests and Procedures

Patients with acanthosis nigricans often receive complete physical skin exam performed (ml), hematologic tests, lipid panel, hemoglobin a1c measurement, glucose measurement, depression screen, examination of breast and physical therapy exercises .

Common Medications

The most commonly prescribed drugs for patients with acanthosis nigricans include tretinoin topical, budesonide, alfuzosin (uroxatral), human papillomavirus vaccine (hpv), balsalazide, benzoyl peroxide-erythromycin topical, barium sulfate, tacrolimus topical product, lactic acid topical, multivitamin with minerals, nonoxynol 9 topical, levonorgestrel and terbinafine topical .

Who is at risk?

Groups of people at highest risk for acanthosis nigricans include race/ethnicity = hispanic, age 5-14 years, race/ethnicity = black and age 15-29 years.

Age

< 1 years
0.3x
1-4 years
0.2x
5-14 years
6.2x
15-29 years
1.7x
30-44 years
0.2x
45-59 years
0.2x
60-74 years
0.2x
75+ years
0.1x

Sex

Male
1.0x
Female
1.0x

Race/Ethnicity

Black
1.6x
Hispanic
2.4x
White
0.4x
Other
1.4x
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