Brand names: [2,3-Dichloro-4-(2-Methylene-1-Oxobutyl)Phenoxy]Acetic Acid, Ea, and Edecrin
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
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