A progressive loss, over months to years, of the kidneys' ability to filter blood and produce urine. The most common causes are persistent high blood pressure and uncontrolled diabetes.
A lowered number of red blood cells (the cells that carry oxygen to the tissues) due to some form of kidney disease, such as chronic kidney disease due to high blood pressure. This is caused by lower amounts of a hormone (erythropoietin) produced by the kidneys that tells the body to make red blood cells.